Welcome to the Greenberg Lab

The Greenberg lab focuses on how cytoskeletal molecular motors function in both health and disease. Currently, the lab is studying mutations that cause familial cardiomyopathies, the leading cause of sudden cardiac death in people under 30 years old. The lab uses an array of biochemical, biophysical, and cell biological techniques to decipher how these mutations affect heart contraction from the level of single molecules to the level of engineered tissues. We are also developing new technologies to model contractile diseases across multiple scales of organization. Insights into the disease pathogenesis will guide efforts to develop novel therapies.