Recent Publications

For a complete list, click here :

    • Woody MS, Greenberg MJ, Barua B, Winkelmann DA, Ostap EM. Positive Cardiac Inotrope, Omecamtiv Mecarbil, Activates Muscle Despite Suppressing the Myosin Working Stroke. Nat Commun. Sep 21;9(1):3838 (2018).[Abstract]
    • Greenberg MJ, Daily NJ, Wang A, Conway MK, Wakatsuki T. Genetic and Tissue Engineering Approaches to Modeling the Mechanics of Human Heart Failure for Drug Discovery. Front Cardiovasc Med. Sep 19;5:120. (2018). [Abstract]
    • Greenberg MJ, Shuman H, Ostap EM. Measuring the Kinetic and Mechanical Properties of Non-processive Myosins Using Optical Tweezers. Methods Mol Biol. 1486:483-509 (2017). [Abstract]
    • Woody MS, Lewis JH, Greenberg MJ, Goldman YE, Ostap EM. MEMLET: An Easy-to-Use Tool for Data Fitting and Model Comparison Using Maximum-Likelihood Estimation. Biophysical Journal. 111(2):273-82 (2016). [Abstract]
    • Greenberg, M.J., Arpag, G., Tuzel, E. and Ostap, E.M. A perspective on the role of myosins as mechanosensors. Biophysical Journal 110:2568-2576 (2016). [Abstract]
    • Kee, A.J., Yang, L., Lucas, C.A., Greenberg, M.J., Martel, N., Leong, G.M., Hughes, W.E., Cooney, G.J., James, D.E., Ostap, E.M., Han, W., Gunning, P.W. and Hardeman, E.C. An actin filament population defined by the tropomyosin Tpm3.1 regulates glucose uptake. Traffic (Copenhagen, Denmark). 16:691-711 (2015). [Abstract]
    • Greenberg, M.J., Lin, T., Shuman, H. and Ostap, E.M. Mechanochemical tuning of myosin-I by the N-terminal region. PNAS 112:E3337-E3344 (2015). [Abstract]
    • Greenberg, M.J., Shuman, H. and Ostap, E.M. Inherent force-dependent properties of β-cardiac myosin contribute to the force-velocity relationship of cardiac muscle. Biophysical Journal 107:L41-4 (2014). [Abstract]
    • Shuman, H., Greenberg, M.J., Zwolak, A., Lin, T., Sindelar, C.V., Dominguez, R. and Ostap, E.M. A vertebrate myosin-I structure reveals unique insights into myosin mechanochemical tuning. PNAS 111:2116-2121 (2014). [Abstract]
    • Greenberg, M.J. and Ostap, E.M. Regulation and control of myosin-I by the motor and light chain-binding domains. Trends in Cell Biology. 23:81-9 (2013). [Abstract]
    • Greenberg, M.J., Lin, T., Goldman, Y.E., Shuman, H. and Ostap, E.M. Myosin IC generates power over a range of loads via a new tension-sensing mechanism. PNAS. 109:E2433-E2440 (2012). [Abstract]
    • Lewis, J.H., Greenberg, M.J., Laakso, J.M., Shuman, H. and Ostap, E.M. Calcium regulation of myosin-I tension sensing. Biophysical J. 102:2799-2807 (2012). [Abstract]
    • Chen, C., Greenberg, M.J., Laakso, J.M., Ostap, E.M., Goldman, Y.E and Shuman, H. Kinetic schemes for post-synchronized single molecule dynamics. Biophys J. 102:L23-L25 (2012). [Abstract]
    • Lin, T., Greenberg, M.J., Moore, J.R. and Ostap, E.M. A hearing loss-associated myo1c mutation (R156W) decreases the myosin duty ratio and force sensitivity. Biochemistry 50:1831-1838 (2011). [Abstract]
    • Greenberg, M.J., Kazmierczak, K., Szczesna-Cordary, D. and Moore JR. Cardiomyopathy-linked myosin regulatory light chain mutations disrupt myosin strain-dependent biochemistry. Proc Natl Acad Sci U S A 107:17403-17408 (2010). [Abstract]