2018 Presentations

Date

Presenter

Paper

1/18/18

Introduction

Andrea Soranno

1/25/18

Short form presentations

2/1/18

Drake Jensen

Le TT, Yang Y, Tan C, Suhanovsky MM, Fulbright RM Jr., Inman JT, Li M, Lee J, Perelman S, Roberts JW, Deaconescu AM, Wang MD. Mfd Dynamically Regulates Transcription via a Release and Catch-Up Mechanism. Cell. 2018 Jan 11;172(1-2):344-357.e15. doi: 10.1016/j.cell.2017.11.017. Epub 2017 Dec 7. PubMed PMID: 29224782; PubMed Central PMCID: PMC5766421.

2/8/18

Linxuan Hao

Kilic S, Felekyan S, Doroshenko O, Boichenko I, Dimura M, Vardanyan H, Bryan LC, Arya G, Seidel CAM, Fierz B. Single-molecule FRET reveals multiscale chromatin dynamics modulated by HP1α. Nat Commun. 2018 Jan 16;9(1):235. doi:10.1038/s41467-017-02619-5. PubMed PMID: 29339721; PubMed Central PMCID: PMC5770380.

2/15/18

Victoria Rogers

Jansen S, Collins A, Chin SM, Ydenberg CA, Gelles J, Goode BL. Single-molecule imaging of a three-component ordered actin disassembly mechanism. Nat Commun. 2015 May 21;6:7202. doi: 10.1038/ncomms8202. PubMed PMID: 25995115; PubMed Central PMCID: PMC4443854.

2/22/18

Short form presentations

3/1/18

Min Kyung Shinn

Kirkness MWH, Forde NR. Single-Molecule Assay for Proteolytic Susceptibility: Force-Induced Collagen Destabilization. Biophys J. 2018 Feb 6;114(3):570-576. doi: 10.1016/j.bpj.2017.12.006. PubMed PMID: 29414702.

3/8/18

Sarah Clippinger

Robison P, Caporizzo MA, Ahmadzadeh H, Bogush AI, Chen CY, Margulies KB, Shenoy VB, Prosser BL. Detyrosinated microtubules buckle and bear load in contracting cardiomyocytes. Science. 2016 Apr 22;352(6284):aaf0659. doi:10.1126/science.aaf0659. PubMed PMID: 27102488; PubMed Central PMCID: PMC5441927.

3/15/18

Nicole Fazio

Craig JM, Laszlo AH, Brinkerhoff H, Derrington IM, Noakes MT, Nova IC, Tickman BI, Doering K, de Leeuw NF, Gundlach JH. Revealing dynamics of helicase translocation on single-stranded DNA using high-resolution nanopore tweezers. Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):11932-11937. doi:10.1073/pnas.1711282114. Epub 2017 Oct 16. PubMed PMID: 29078357; PubMed Central PMCID: PMC5692567.

3/22/18

Jasmine Cubuk

CJepsen MDE, Sparvath SM, Nielsen TB, Langvad AH, Grossi G, Gothelf KV, Andersen ES. Development of a genetically encodable FRET system using fluorescent RNA aptamers. Nat Commun. 2018 Jan 2;9(1):18. doi: 10.1038/s41467-017-02435-x. Erratum in: Nat Commun. 2018 Feb 9;9(1):669. PubMed PMID: 29295996; PubMed Central PMCID: PMC5750238.

3/29/18

Short form presentations

4/5/18

Ginger Johnson

Kondo T, Pinnola A, Chen WJ, Dall’Osto L, Bassi R, Schlau-Cohen GS. Single-molecule spectroscopy of LHCSR1 protein dynamics identifies two distinct states responsible for multi-timescale photosynthetic photoprotection. Nat Chem. 2017 Aug;9(8):772-778. doi: 10.1038/nchem.2818. Epub 2017 Jul 17. PubMed PMID:28754946.

4/19/18

Yerdos Ordabayev

Chen JS, Dagdas YS, Kleinstiver BP, Welch MM, Sousa AA, Harrington LB, Sternberg SH, Joung JK, Yildiz A, Doudna JA. Enhanced proofreading governs CRISPR-Cas9 targeting accuracy. Nature. 2017 Oct 19;550(7676):407-410. doi:10.1038/nature24268. Epub 2017 Sep 20. PubMed PMID: 28931002.

4/26/18

Short form presentations

5/3/18

Josh Brettmann

Rosholm KR, Baker MA, Ridone P, Nakayama Y, Rohde PR, Cuello LG, Lee LK, Martinac B. Activation of the mechanosensitive ion channel MscL by mechanical stimulation of supported Droplet-Hydrogel bilayers. Sci Rep. 2017 Mar 27;7:45180. doi: 10.1038/srep45180. PubMed PMID: 28345591; PubMed Central PMCID: PMC5366917.